People

PI: Amanda Larracuente
Graduate Students: Dani Khost, Ching-Ho Chang, Xiaolu Wei
Research associates and technicians: Danna Eickbush, Shaun Jones, Stephanie Hao
Undergraduates: Arif Kodza, Danielle Pascua, Isaac Wong, Taylar Mouton
Former lab members

LarracuenteLab2016 (1)
Larracuente lab 2016

Lab members:


Amanda Larracuente, Ph.D. (Principal Investigator)

e-mail: alarracu@bio.rochester.edu
Amanda earned her Ph.D. studying Drosophila genomics and sex chromosome evolution in Dr. Andrew Clark’s lab at Cornell University. During her postdoctoral training, she focused on the evolution of selfish DNA including the Segregation Distorter system of Drosophila melanogaster.

Selected recent publications. Click here for a full list of Amanda’s publications or see her NCBI bibliography.

Graduate students

Danielle Emerson (Dani) Khost (Ph.D. candidate)

e-mail: dkhost@ur.rochester.edu
Dani is an E2G2 student working on the evolution and functional genomics of satellite DNA in Drosophila species. She is using deep real time single molecule sequencing from Pacific Biosciences to study the structural organization of satellite DNA loci in Drosophila genomes.

Publications:

Ching-Ho Chang (Ph.D. candidate)Ching-HoChang

Ching-Ho is an E2G2 student working on Segregation Distorter in Drosophila melanogaster and Y chromosome evolution in  Drosophila. Before coming to Rochester, Ching-Ho worked with Dr. Chau-Ti Ting  at National Taiwan University on neo-sex chromosome evolution in Drosophila albomicans. Ching-Ho is a recipient of the Ernst Caspari Fellowship.

Selected publications:

Xiaolu Wei (graduate student)

Xiaolu is a Biomedical Genetics student studying how satellite DNA is regulated in the germline using functional genomics and cytogenetics.

Research associates and technicians

Danna Eickbush, Ph.D. (Research associate)

e-mail: danna.eickbush@rochester.eduflowers
Danna Eickbush attended the University of Arizona where she was introduced to the wonders of molecular biology and immediately transferred to the newly formed Department of Cellular and Development Biology. She then joined the Ph.D. program in Cellular and Development Biology at Harvard University, characterizing the molecular structure and transcriptional patterns of the 71C-E region of Drosophila melanogaster while in the lab of Dr. Peter Cherbas. After moving to upstate New York, she did a postdoc with Dr. Jack Werren studying the selfish B-chromosome Paternal Sex Ratio (PSR) in the wasp Nasonia vitripennis. For the last 25 years, she has worked as a research associate with Dr. Tom Eickbush at the University of Rochester. The long tenure with her husband allowed Danna to study many aspects of the life cycle of the retrotransposable element R2, including its regulation and transcription. Danna works on the regulation of satellite DNA expression in Drosophila species.

Selected recent publications. Click here to see Danna’s PubMed list.

 

Stephanie Hao (Technician)

Stephanie joined the lab after graduating from the University of Rochester with a degree in cell and developmental biology. She is working on satellite DNA genetics. Stephanie is also in a masters program in bioinformatics at Johns Hopkins.

 

Shaun Jones (Technician)ShaunJones2

Shaun is a skilled fly wrangler who  maintains the lab’s fly lines and helps the lab with various projects.

 

 

 

Undergraduates

Danielle Pascua (undergraduate)

Danielle is an undergraduate technician using genetics to study Segregation Distorter.

 

 

 

Isaac Wong (undergraduate)

Isaac is using computational and cytogenetic methods to study repeat evolution in fireflies.

 

 

 

 

Arif Kodza (undergraduate)Arif

Arif is studying the population genetics of satellite DNAs in Drosophila genomes.

 

 

 

Taylar Mouton (undergraduate)

Taylar is studying the function of multi-copy Y-linked gene families in D. melanogaster and the simulans clade species.

 

 

Former lab members

Undergraduates: Christian Silva (current grad student UC Davis), Thanatcha (Kwan) Khunkhet, Linhe (Alex) Xu (grad student at Vanderbilt starting fall 2017)

Graduate students: Steven Messer (rotating grad student), John Bettinger (rotating grad student)