Tim Baran
The Institute of Optics
Methylene blue mediated photodynamic therapy: pre-clinical results and spectroscopic studies
Tuesday, July 13, 2010
12 – 12:30 PM
Goergen 101
Photodynamic Therapy (PDT) is an emerging cancer therapy that uses a combination of photosensitive drugs and targeted irradiation to destroy tumors. A number of photosensitizers have been examined, which I will give a brief overview of. In addition to providing the mechanism for PDT, most of these photosensitizers are naturally fluorescent. This provides an excellent opportunity for spectroscopic monitoring and dosimetry.
We have chosen to work with the photosensitizer methylene blue, due to its low cost and widespread availability. I will present the results of a study in mice that we have recently completed in which various treatment parameters were examined. Preliminary spectroscopic results will also be presented.
Bring your lunch at the talk; we will offer the dessert!
